Ceroli’s production features natural and humble materials, particularly untreated wood, but also fabric, plastic or aluminium. His creations, which are sometimes polychrome and serialized, represent common objects, such as numbers, letters of the alphabet, human figures, and allusions to Leonardo da Vinci and other masters of the Italian Renaissance.   He began to experiment with new materials, particularly with raw wood, such as Russian pinewood. He used these materials to create silhouetted shapes in his furniture and objects that related simplistically to the surrounding space. Ceroli relates back to the traditional medieval craftsmen, focusing on an overall and overwhelming attraction that holds a dialogue with the spectator.  

In 1966 he gained international recognition by winning a prize at the Venice Biennale for the Cassa Sistina, an architectonic work conceived as an open dialogue with the public and marking a transition into an art that engaged with its surroundings.  In 1967-1968 he exhibited alongside other artists adhering to the Arte Povera and Italian Pop Art poetics.

Throughout the years, Ceroli undertook the decoration of many public spaces, such as the churches of Santa Maria Madre del Redentore di Tor Bella Monaca in Rome (1987) and San Carlo Borromeo in Naples (1990). He also works as a theatre scenographer, cooperating with the likes of Teatro Stabile in Turin (1968), La Scala in Milan (1971) and Teatro La Fenice in Venice (2018).

In the 1970's and 1980's he experimented with polychrome marble, glass, powder and bronze, revisiting artworks from the Renaissance to the present day. Ceroli’s interest in  these various disciplines led him to transcend the boundaries of the mere work of art, and to explore how it interacts with other fields, such as architecture or theatre. Creating his own working and living environment, he gathered more than 500 works in a museum-like space. This was meant to improve and grow constantly and was imagined to inspire positively the new generations of artists.

Ceroli's designs are dramatic and sculptural, with exaggerated forms and bold lines and often paying tribute to historical artworks. One of Ceroli's major works was his 'Mobili nella Valle' series, inspired directly by De Chirico's 1927 painting of the same name. Ceroli's sculpture, a direct homage to De Chirico's painting, sold on the 13th May 2015 at Phillips New York with a $400,000 - $600,000 estimate. This value sets a precedent for Ceroli furniture, however furniture from this series is likely to follow suit.

His works are displayed at the National Gallery of Modern and Contemporary Art in Rome, the Museum of Modern Art in New York City and the Mississippi Museum of Art in Jackson, Mississippi. One of his sculptures is on the Luigi Einaudi campus of the University of Turin, and another one is at the Vatican Museums.   Ceroli lives and works in Rome, where he also continues to work as a set designer.